Pulmonary Sarcomas in a Young Chicken

作者: Scott Hafner , Mark A. Goodwin , E. J. Smith , Aly Fadly , Lynda C. Kelley

DOI: 10.2307/1592724

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摘要: SUMMARY. Both lungs of a 5-wk-old broiler chicken contained miliary, round, white tumors. Microscopically, these masses were composed compactly arranged cells with round to oval nuclei and indistinct cytoplasmic borders. Immunohistochemically, tumor positive for vimentin but negative cytokeratin, S-100 protein, neuron-specific enolase, smooth muscle actin, muscle-specific actin. Ultrastructurally, separated by collagen bands some fibrils. These results suggest that the primitive mesenchymal composing sarcomas may have originated from precursors interstitial or fibroblasts interparabronchial interatrial septa. DNA was extracted paraffin-embedded tissues probed sequences specific Marek's disease virus, reticuloendotheliosis viruses, exogenous avian leukosis subgroup J viruses. Only viruses identified in tumors surrounding lung. RESUMEN. Reporte de Caso--Sarcomas pulmonares en un polio engorde joven. Ambos pulmones 5 semanas edad contenian tumores granulosos, redondos y blancos. Microsc6picamente estas masas tumorales estaban compuestas cdlulas dispuestas forma compacta con nicleos u ovales bordes citoplhsmicos indiferenciados. Inmunohistoquimicamente, las fueron positivas para la vimentina pero negativas citoqueratina, proteina S-100, enolasa neurona especifica, actina del misculo liso especifica. Ultraestructuralmente, c'lulas separadas por bandas coligeno algunas fibrillas colagenosas. Estos resultados sugieren que mesenquimales primitivas componen estos pueden haberse originado precursores intersticiales o fibroblastos septo interparabronquial interatrial. El fue extraido tejidos fijados parafina examinado sondas especificas enfermedad Marek, reticuloendoteliosis, virus ex6geno leucosis subgrupo leucosis. S61o secuencias los identificadas el pulm6n adyacente.

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