Pathogenetic Impact of Bacterial-Fungal Interactions.

摘要: Polymicrobial infections are of paramount importance because the potential severity clinical manifestations, often associated with increased resistance to antimicrobial treatment. The intricate interplay host and immune system, impact on microbiome imbalance, in this context. equilibrium microbiota human is critical for preventing dysbiosis ensuing development disease. Bacteria fungi can communicate via signaling molecules, produce metabolites toxins capable modulating response or altering efficacy Most bacterial–fungal interactions described date focus fungal pathogen Candida albicans different bacteria. In review, we discuss more than twenty involving several clinically important pathogens. interactions, which be synergistic antagonistic, both vitro vivo, addressed a quorum-sensing molecules produced, outcome.