Methicillin-resistant Staphylococcus aureus prevalence: Current susceptibility patterns in Trinidad

摘要: Methicillin-resistant Staphylococcus aureus (MRSA) has become one of the most widespread causes nosocomial infections worldwide. Recently, reports have emerged that S. strains recovered from community-acquired are also methicillin-resistant. This study was undertaken to analyze prevalence methicillin resistance among isolates at a regional hospital in Trinidad, and document current profile MRSA methicillin-sensitive (MSSA) commonly used anti-staphylococcal agents. Over 6-year period we analyzed 2430 various clinical sources, community practices. Antimicrobial susceptibility testing done according guideline recommendations National Committee for Clinical Laboratory Standards. The surgical/burn wounds, urine pus/abscess were 60.1%, 15.5% 6.6%, respectively. major sources MSSA upper respiratory tract specimens with rates 32.9%, 17.1% 14.3%, greatest seen erythromycin (86.7%), clindamycin (75.3%). Resistance highest ampicillin (70%). tetracycline similar both (78.7%) (73.5%). recovery (20.8%) significantly higher than previous years (12.5%) (p < 0.001), whereas relatively same (4.1% versus 8.1%). increased 12.5% 1999 20.8% 2004. Most associated infected wounds which may via hands HCPs during dressing exercises. Infection control measures aimed proper hand hygiene procedures interrupt spread MRSA. be carriers their anterior nares. Surveillance cultures patients help identify who would offered antibiotics eradicate organisms. resistant several non-β-lactam antibiotics. Frequent monitoring patterns formulation definite antibiotic policy maybe helpful decreasing incidence infection.