Correlation of nerve ultrasound, electrophysiological and clinical findings in chronic inflammatory demyelinating polyneuropathy.

作者: A. Kerasnoudis , K. Pitarokoili , V. Behrendt , R. Gold , M.-S. Yoon

DOI: 10.1111/JON.12079

关键词:

摘要: BACKGROUND AND PURPOSE We present the nerve ultrasound findings in chronic inflammatory demyelinating polyneuropathy (CIDP) and examine their correlation with electrophysiology functional disability. METHODS A total of 75 healthy controls 48 CIDP patients underwent clinical, sonographic electrophysiological evaluation a mean 3.9 years(SD+/−2.7) after disease onset. RESULTS Nerve revealed statistically significant higher cross-sectional area (CSA) values median (P<.0001), ulnar radial tibial fibular nerve(P<.0001) most anatomic sites brachial plexus (supraclavicular, P<.0001;interscalene space, P = .0118),when compared to controls. The electroneurography documented signs permanent axonal loss majority peripheral nerves. A between was found only motor conduction velocity CSA at ankle (r −.451, .007). Neither sonography nor correlated disability. carpal tunnel Guyon's canal duration (P .036, .027 respectively). DISCUSSION CIDP seems show inhomogenous enlargement nerves, weak findings. disability patients. Multicenter, prospective studies are required proof applicability diagnostic these

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