摘要: The purpose of this chapter is to describe the genetic background and terminology essential for an understanding toxicology. It necessary appreciate basic structure target molecule, DNA, understand how it operates, since types molecular lesions that chemicals induce in molecule effects they generate are intimately tied function molecule. Because unique position held by DNA maintaining processing cellular information, intrinsic capacity self-repair appears have evolved simultaneously with environmental adaptation Repair processes also believed influence kinetics mutation induction preventing many chemically induced from becoming fixed as permanent alterations.