Colorectal cancer and race: understanding the differences in outcomes between African Americans and whites.

摘要: Understanding the differences in incidence and mortality rate between African Americans whites with CRC remains a perplexing problem. There is clearly not any one factor that explains observed differences. Clinicians are just beginning to understand importance of tumor biology, genetics, lifestyle risk factors explaining how CRCs present they behave. This holds true regardless patient's race, sex, or age. Whether these will add disproportionately understanding racial presentation outcome be seen. Certainly, issues surrounding screening for remain important advanced stage Americans. In particular, better needed who being screened why. For example, higher-risk if what reasons this? Importantly, even were able eliminate at whites, survival disadvantage, albeit much smaller one, would likely persist. Clearly, there need why receiving recommended therapy same as whites. becomes more life-prolonging options treating both localized metastatic colon cancer continue multiply. Finally, apparent greater disparity have II disease should explored detail, because this could an immediate impact on treatment recommendations. 23-gene signature was recently found predictive recurrence among patients Dukes B [66]. If model validated further studies, look whether African-American signature. The problem has been defined: higher from than task now disparities ultimately come up workable solutions so amazing progress benefits all groups country.