Modelling the air mass transfer in a healthy and a stented rabbit trachea: CT-images, computer simulations and experimental study ☆
作者： M. Malvè , C. Serrano , E. Peña , R. Fernández-Parra , F. Lostalé
DOI: 10.1016/J.ICHEATMASSTRANSFER.2014.02.001
关键词:
摘要: Abstract Endotracheal stenting is a controversial treatment for tracheal stenosis. Metallic stents have advantages but also show disadvantages such as restenosis due to epithelial hyperplasia and granuloma formation. In this work we analyze the response of rabbit wall during normal breathing under implantation Zilver® Flex™ Stent. Trachea geometries were reconstructed using medical images both healthy stented rabbit. The numerical model was used analyzing stresses before after prosthesis fluid–structure interaction approach (FSI). Unstructured tetrahedral-based grids perform simulations with finite element-based commercial software code. Experimental tests on trachea samples performed in order get material property constants. Deformations cartilage rings muscular membrane well maximum principal analyzed compared those absence prosthesis. addition, an experimental validation provided. percutaneously implanted fluoroscopic control. Period study 90 days. assessed by means computerized tomography endoscopy, macroscopic findings histopathological study. Experimentally revealed tissue damages stent then results. Interesting correlation maximal induced shear stress found same region.
sci-hub.se 参考文章(56)
Laudanski J, Chyczewska E, Mroz Rm, Kozlowski, Bondyra Z, Dabrowski A, Kordecki K, Baniukiewicz A, Lewszuk A, Severe respiratory distress caused by central airway obstruction treated with self-expandable metallic stents. Journal of Physiology and Pharmacology. ,vol. 59, pp. 491- 497 ,(2008)
MA De Gregorio, J Medrano, ER Alfonso, J Fernández, C Ruiz, H Vallés, FJ Suárez, None, Estado actual y experiencia clínica en el tratamiento de las estenosis traqueobronquiales con prótesis metálicas autoexpandibles Archivos de Bronconeumología. ,vol. 33, pp. 509- 514 ,(1997) , 10.1016/S0300-2896(15)30533-0
H.Y. Luo, Y Liu, Modeling the bifurcating flow in a CT-scanned human lung airway Journal of Biomechanics. ,vol. 41, pp. 2681- 2688 ,(2008) , 10.1016/J.JBIOMECH.2008.06.018
Brendan P. Madden, Tuck-Kay Loke, Abhijat C. Sheth, Do Expandable Metallic Airway Stents Have a Role in the Management of Patients With Benign Tracheobronchial Disease The Annals of Thoracic Surgery. ,vol. 82, pp. 274- 278 ,(2006) , 10.1016/J.ATHORACSUR.2006.02.028
Claudio Chiastra, Stefano Morlacchi, Simon Pereira, Gabriele Dubini, Francesco Migliavacca, Computational fluid dynamics of stented coronary bifurcations studied with a hybrid discretization method European Journal of Mechanics B-fluids. ,vol. 35, pp. 76- 84 ,(2012) , 10.1016/J.EUROMECHFLU.2012.01.011
Fei Sun, Jesús Usón, Javier Ezquerra, Verónica Crisóstomo, Laura Luis, Manuel Maynar, Endotracheal stenting therapy in dogs with tracheal collapse Veterinary Journal. ,vol. 175, pp. 186- 193 ,(2008) , 10.1016/J.TVJL.2007.01.011
M. Malvè, S. Chandra, J. L. López-Villalobos, E. A. Finol, A. Ginel, M. Doblaré, CFD analysis of the human airways under impedance-based boundary conditions: Application to healthy, diseased and stented trachea Computer Methods in Biomechanics and Biomedical Engineering. ,vol. 16, pp. 198- 216 ,(2013) , 10.1080/10255842.2011.615743
Hitinder S. Gurm, Thomas Boyden, Kathy B. Welch, Comparative safety and efficacy of a sirolimus-eluting versus paclitaxel-eluting stent: a meta-analysis. American Heart Journal. ,vol. 155, pp. 630- 639 ,(2008) , 10.1016/J.AHJ.2007.11.021
R.K. Calay, Jutarat Kurujareon, Arne Erik Holdø, Numerical simulation of respiratory flow patterns within human lung. Respiratory Physiology & Neurobiology. ,vol. 130, pp. 201- 221 ,(2002) , 10.1016/S0034-5687(01)00337-1
Hubert Hautmann, Martin Bauer, Klaus J Pfeifer, Rudolf M Huber, Flexible bronchoscopy: a safe method for metal stent implantation in bronchial disease The Annals of Thoracic Surgery. ,vol. 69, pp. 398- 401 ,(2000) , 10.1016/S0003-4975(99)01398-3