Highly stereoselective synthesis of indanes with four stereogenic centers via sequential Michael reaction and [3+2] cycloaddition
作者： Pei Juan Chua , Bin Tan , Limin Yang , Xiaofei Zeng , Di Zhu
DOI: 10.1039/C0CC01577F
关键词:
摘要: A highly efficient organocatalytic sequential reaction involving Michael addition of bis(phenylsulfonyl)ethylene, in situ condensation and intramolecular nitrone [3+2] cycloaddition with a variety aldehydes hydroxyamines to afford single diastereomer indanes four stereogenic centers excellent yields stereoselectivities was developed.
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