Effective binding to protein antigens by antibodies from antibody libraries designed with enhanced protein recognition propensities
作者： Jhih-Wei Jian , Hong-Sen Chen , Yi-Kai Chiu , Hung-Pin Peng , Chao-Ping Tung
DOI: 10.1080/19420862.2018.1550320
关键词:
摘要: Antibodies provide immune protection by recognizing antigens of diverse chemical properties, but elucidating the amino acid sequence-function relationships underlying specificity and affinity o...
sci-hub.se 参考文章(52)
Eric J Sundberg, Roy A Mariuzza, Molecular recognition in antibody-antigen complexes. Advances in Protein Chemistry. ,vol. 61, pp. 119- 160 ,(2002) , 10.1016/S0065-3233(02)61004-6
Hong-Sen Chen, Shin-Chen Hou, Jhih-Wei Jian, King-Siang Goh, San-Tai Shen, Yu-Ching Lee, Jhong-Jhe You, Hung-Pin Peng, Wen-Chih Kuo, Shui-Tsung Chen, Ming-Chi Peng, Andrew H-J Wang, Chung-Ming Yu, Ing-Chien Chen, Chao-Ping Tung, Tzu-Han Chen, Kuo Ping Chiu, Che Ma, Chih Yuan Wu, Sheng-Wei Lin, An-Suei Yang, None, Predominant structural configuration of natural antibody repertoires enables potent antibody responses against protein antigens. Scientific Reports. ,vol. 5, pp. 12411- 12411 ,(2015) , 10.1038/SREP12411
Saswati Panda, Jeak L. Ding, Natural Antibodies Bridge Innate and Adaptive Immunity Journal of Immunology. ,vol. 194, pp. 13- 20 ,(2015) , 10.4049/JIMMUNOL.1400844
Jordan D. Dimitrov, Cyril Planchais, Lubka T. Roumenina, Tchavdar L. Vassilev, Srinivas V. Kaveri, Sebastien Lacroix-Desmazes, Antibody Polyreactivity in Health and Disease: Statu Variabilis Journal of Immunology. ,vol. 191, pp. 993- 999 ,(2013) , 10.4049/JIMMUNOL.1300880
Gopalan Raghunathan, Jason Smart, Joseph Williams, Juan Carlos Almagro, Antigen-binding site anatomy and somatic mutations in antibodies that recognize different types of antigens. Journal of Molecular Recognition. ,vol. 25, pp. 103- 113 ,(2012) , 10.1002/JMR.2158
Marc H. V. Van Regenmortel, Specificity, polyspecificity, and heterospecificity of antibody-antigen recognition Journal of Molecular Recognition. ,vol. 27, pp. 627- 639 ,(2014) , 10.1002/JMR.2394
Sara Birtalan, Yingnan Zhang, Frederic A. Fellouse, Lihua Shao, Gabriele Schaefer, Sachdev S. Sidhu, The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies. Journal of Molecular Biology. ,vol. 377, pp. 1518- 1528 ,(2008) , 10.1016/J.JMB.2008.01.093
Benjamin North, Andreas Lehmann, Roland L. Dunbrack, A New Clustering of Antibody CDR Loop Conformations Journal of Molecular Biology. ,vol. 406, pp. 228- 256 ,(2011) , 10.1016/J.JMB.2010.10.030
William Dall'Acqua, Ellen R. Goldman, Edward Eisenstein, Roy A. Mariuzza, A Mutational Analysis of the Binding of Two Different Proteins to the Same Antibody Biochemistry. ,vol. 35, pp. 9667- 9676 ,(1996) , 10.1021/BI960819I
Jordan R. Willis, Bryan S. Briney, Samuel L. DeLuca, James E. Crowe, Jens Meiler, Human Germline Antibody Gene Segments Encode Polyspecific Antibodies PLoS Computational Biology. ,vol. 9, pp. e1003045- ,(2013) , 10.1371/JOURNAL.PCBI.1003045