Amatoxin-conjugates with improved linkers

作者: Jan Anderl , Werner Simon , Christian Lutz , Christoph Müller

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摘要: The invention relates to tumour therapy. In one aspect, the present conjugates of an amatoxin and a target-binding moiety, e.g. antibody, connected by linker comprising urea which are useful in treatment cancer. further aspect pharmaceutical compositions such conjugates.

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