Inflammatory bowel disease: new insights into pathogenesis and treatment

摘要: Despite all the advances in our understanding of pathophysiology inflammatory bowel disease (IBD), we do not know cause. Some most recently available data have been discussed here and yet it is now becoming increasingly accepted that immunogenetics play an important role predisposition, modulation, perpetuation IBD. The mucosal immune system central effector intestinal inflammation injury, with cytokines playing a modulating inflammation. milium, enteric flora particular, appears to be greater significance than previously held. A review made main areas research exploring mechanisms more intimately associated development IBD, providing agents currently used, identifying host new therapeutic potentially interacting or interrupting specific targets genesis