Ergotism and Photosensitization in Swine Produced by the Combined Ingestion of Claviceps Purpurea Sclerotia and Ammi Majus Seeds

摘要: Poisoning of domestic animals happens frequently in the southeast Buenos Aires Province (Argentina). Intoxications are produced mainly by ingestion plants and mycotoxins, but rarely affected simultaneously both types agents. One herd pigs suffered simultaneous intoxications ergot alkaloids from Claviceps purpurea sclerotia furocoumarins Ammi majus seeds. Pigs were fed a diet composed wheat (poor quality) or corn protein vitamin supplements. This was completed with forage sorghum. Nervous signs first observed 5-7 days after initiation feeding suspect ration. These followed cutaneous irritation. Snout ulcers, eyelid edema, conjunctivitis several piglets. Ten start incriminated ration, 8 abortions observed. Many sows that nursing piglets developed udder edema teat cracking. Dermal lesions most unpigmented areas skin not Duroc-Jersey boar. Removal another prepared good-quality allowed all to recover 15 days. The experienced normal pregnancies parturitions, litter sizes, piglet weights when cleaned portion poor-quality wheat. No photosensitization Examination impurities suspected indicated presence 2.2% A. seeds 0.14% C. sclerotia. quantitative analysis 3.2 g xanthotoxin 0.65 bergaptene/100 0.73 (expressed as ergonovine) per 100 Qualitative demonstrated ergotamine, ergocristine, ergonovine. results indicate clinical caused large quantities these biologically active compounds.