Sustainable Resource based Hyperbranched Epoxy Nanocomposite as an Infection Resistant, Biodegradable, Implantable Muscle Scaffold

作者: Shaswat Barua , Bhaskarjyoti Gogoi , Lipika Aidew , Alak K. Buragohain , Pronobesh Chattopadhyay

DOI: 10.1021/ACSSUSCHEMENG.5B00069

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摘要: Use of sustainable resources in the realm materials science has opened newer possibilities for fabricating biodegradable biomaterials. Cellulose is an abundantly available bioresource that proved excellent potential composite and biomaterials domain. Hence, this report potentiality a “green” CuO–nanofibrillar cellulose/glycerol based hyperbranched epoxy nanocomposite was presented as implantable muscle tissue scaffold. Muscles reconstruction been longstanding problem medical science. However, with evolution polymeric scaffolds, repairing damaged or lost tissues becomes possible aid engineering. The prepared material possessed high mechanical properties (tensile strength 55 MPa) to support cell growth. In vitro studies revealed could growth proliferation L6 cells, without causing any detriment their cellular morphology. Further, both vivo toxicity assessments established p...

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