Chloroquine and hydroxychloroquine in the treatment of malaria and repurposing in treating COVID-19.
作者： Zi-Ning Lei , Zhuo-Xun Wu , Shaowei Dong , Dong-Hua Yang , Litu Zhang
DOI: 10.1016/J.PHARMTHERA.2020.107672
关键词:
摘要: Chloroquine (CQ) and Hydroxychloroquine (HCQ) have been commonly used for the treatment prevention of malaria, autoimmune diseases several decades. As their new mechanisms actions are identified in recent years, CQ HCQ wider therapeutic applications, one which is to treat viral infectious diseases. Since pandemic coronavirus disease 2019 (COVID-19), subjected a number vitro vivo tests, prospects COVID-19 proposed. In this article, applications action conventional fields anti-malaria anti-rheumatism, as well repurposing anti-virus reviewed. The current trials future potential combating discussed.
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