How leukocytes cross the vascular endothelium

摘要: Immune responses depend on the ability of leukocytes to move from circulation into tissue. This is enabled by mechanisms that guide right exit sites and allow them cross barrier blood vessel wall. process regulated a concerted action between endothelial cells leukocytes, whereby activate direct extravasation sites, in turn instruct open path for transmigration. Review focuses recently described control routes through barrier.