Practical grouping of positive lymph nodes in pancreatic head cancer treated by an extended pancreatectomy

作者: Osamu Ishikawa , Hiroaki Ohigashi , Yo Sasaki , Toshiyuki Kabuto , Hiroshi Furukawa

DOI: 10.1016/S0039-6060(97)90352-4

关键词:

摘要: Background. Until recently long-term survival has not been expected when at least one positive node was detected any site in pancreatic head cancer treated by conventional pancreatectomy. However, even nodal involvement is seen, there an increasing number of survivors after extended pancreatectomy which a wide range lymphatic and connective tissues were cleared.1 Thus the purpose present study to establish practical rational grouping lymph nodes pancreatectomy. Methods. In 81 patients who tolerated for head, mean 56 ± 23 (range, 28 89) each patient examined under microscope determine presence or absence cancer. They classified anatomically into 14 groups, incidence, distribution, examined. A simplified made on basis histologic findings checked against rates. Results. Nodal 59 (73%) patients, more commonly observed posterior pancreaticoduodenal (PPD), superior mesenteric (SM), anterior (APD) groups than 11 other (p < 0.05). The PPD, APD, SM offered sole sites with incidence levels 23%, 17%, 6%, respectively, whereas none did. four groups: (a), negative all (n = 22); (b), but limited PPD/APD 14); (c), also group, 13); (d), 32). This classification associated well 5-year rate: 59% group 53% 15% 0% (d) [p 0.05; (b) versus (c)]. Also this total rate three 47% 6% seven 0.05). Conclusions. clinicopathologic staging spread from carcinoma PPD APD considered first stations metastasis, 12 groups—including group—were categorized as second distant stations.

参考文章(10)
TNM classification of malignant tumours Published in <b>2010</b> in Chichester, West Sussex, UK ;Hoboken, NJ by Wiley-Blackwell. ,(1987) , 10.1007/978-3-642-82982-6
Charles J. Yeo, John L. Cameron, Keith D. Lillemoe, James V. Sitzmann, Ralph H. Hruban, Steven N. Goodman, William C. Dooley, JoAnn Coleman, Henry A. Pitt, Pancreaticoduodenectomy for cancer of the head of the pancreas: 201 patients Annals of Surgery. ,vol. 221, pp. 721- 733 ,(1995) , 10.1097/00000658-199506000-00011
Thomas C. Böttger, Stefan Störkel, Stefan Wellek, Michael Stöckle, Theo Junginger, Factors influencing survival after resection of pancreatic cancer. A DNA analysis and a histomorphologic study. Cancer. ,vol. 73, pp. 63- 73 ,(1994) , 10.1002/1097-0142(19940101)73:1<63::AID-CNCR2820730113>3.0.CO;2-P
Antonio L. Cubilla, Joseph Fortner, Patrick J. Fitzgerald, Lymph node involvement in carcinoma of the head of the pancreas area Cancer. ,vol. 41, pp. 880- 887 ,(1978) , 10.1002/1097-0142(197803)41:3<880::AID-CNCR2820410315>3.0.CO;2-J
A. Nakao, A. Harada, T. Nonami, T. Kaneko, H. Murakami, S. Inoue, Y. Takeuchi, H. Takagi, Lymph node metastases in carcinoma of the head of the pancreas region. British Journal of Surgery. ,vol. 82, pp. 399- 402 ,(2005) , 10.1002/BJS.1800820340
Masato Kayahara, Takukazu Nagakawa, Hironobu Kobayashi, Kazuhiro Mori, Tatsuo Nakano, Naotaka Kadoya, Tetsuo Ohta, Keiichi Ueno, Itsuo Miyazaki, Lymphatic flow in carcinoma of the head of the pancreas Cancer. ,vol. 70, pp. 2061- 2066 ,(1992) , 10.1002/1097-0142(19921015)70:8<2061::AID-CNCR2820700808>3.0.CO;2-V
OSAMU ISHIKAWA, HIROAKI OHHIGASHI, Y O SASAKI, TOSHIYUKI KABUTO, ICHIROH FUKUDA, HIROSHI FURUKAWA, SHINGI IMAOKA, TAKESHI IWANAGA, Practical usefulness of lymphatic and connective tissue clearance for the carcinoma of the pancreas head. Annals of Surgery. ,vol. 208, pp. 215- 220 ,(1988) , 10.1097/00000658-198808000-00014
Richard J. Geer, Murray F. Brennan, Prognostic indicators for survival after resection of pancreatic adenocarcinoma. American Journal of Surgery. ,vol. 165, pp. 68- 73 ,(1993) , 10.1016/S0002-9610(05)80406-4
JON R. COHEN, NANCY KUCHTA, NANCY GELLER, G. TOM SHIRES, PETER DINEEN, Pancreaticoduodenectomy: A 40-Year Experience Annals of Surgery. ,vol. 195, pp. 608- 617 ,(1982) , 10.1097/00000658-198205000-00010