作者: Thomas M. Leath , Manav Singla , Stephen P. Peters
DOI: 10.1016/S1359-6446(05)03646-9
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摘要: At present, there are a wide variety of novel and emerging therapeutic approaches for the treatment asthma. Here, we will summarize these state-of-the-art approaches, including specific nonspecific mediator inhibition – quest that has been on going more than 25 years together with cytokine modulation in asthma (primarily attempting to modulate Th2–Th1 balance asthma), targeting cell recruitment, angiogenesis, signal transduction gene pathways. Finally, discuss recently approved anti-IgE therapy allergic immune using CpG oligodeoxynucleotides.