Ethical reflections on pharmacogenetics and DNA banking in a cohort of HIV-infected patients.

摘要: The aim of this study was to analyse ethical issues concerning the storage human biological samples be used in genetic analyses and pharmacogenetic research based on a French experience DNA banking cohort immunodeficiency virus (HIV)-infected patients started protease inhibitor-containing treatment. We describe raised during establishment bank, including questions dealing with autonomy, benefit patient, information sharing confidentiality as well guarantees use DNA. practical applications themes illustrated theoretically literature are discussed. Most points not specific HIV, but some them may more accurate due characteristics HIV population, which is involved social debate through community life increased risk stigmatization. Our results summarized memorandum consent form presented Appendices. One issue still open discussion way data will given patients. This work should allow other researchers members evaluation committees enrich their considerations stimulate topic.