Antibacterial activities of naturally occurring compounds against antibiotic-resistant Bacillus cereus vegetative cells and spores, Escherichia coli, and Staphylococcus aureus.

作者: MENDEL FRIEDMAN , ROBERT BUICK , CHRISTOPHER T. ELLIOTT

DOI: 10.4315/0362-028X-67.8.1774

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摘要: After demonstrating the lack of effectiveness standard antibiotics against acquired antibiotic resistance Bacillus cereus (NCTC 10989), Escherichia coli 1186), and Staphylococcus aureus (ATCC 12715), we showed that following natural substances were antibacterial these resistant pathogens: cinnamon oil, oregano thyme carvacrol, (S)-perillaldehyde, 3,4-dihydroxybenzoic acid (beta-resorcylic acid), 3,4-dihydroxyphenethylamine (dopamine). Exposure three pathogens to a dilution series test compounds oil was most active substance. The oils pure exhibited exceptional activity B. vegetative cells, with being at nanogram per milliliter levels. In contrast, activities spores very low. Activities in approximate order: > approximately carvacrol perillaldehyde dopamine beta-resorcylic acid. order susceptibilities inactivation as follows: (vegetative) >> S. E. (spores). Some may be effective antibiotic-resistant bacteria foods feeds.

参考文章(11)
N. Finley, M. L. Fields, Heat Activation and Heat-induced Dormancy of Bacillus stearothermophilus Spores Applied and Environmental Microbiology. ,vol. 10, pp. 231- 236 ,(1962) , 10.1128/AM.10.3.231-236.1962
David A. Kuhl, Current strategies for managing the patient with sepsis. American Journal of Health-system Pharmacy. ,vol. 59, ,(2002) , 10.1093/AJHP/59.SUPPL_1.S9
C. Economakis, Helen Skaltsa, Costas Demetzos, M. Soković, Costas A. Thanos, Effect of phosphorus concentration of the nutrient solution on the volatile constituents of leaves and bracts of Origanum dictamnus. Journal of Agricultural and Food Chemistry. ,vol. 50, pp. 6276- 6280 ,(2002) , 10.1021/JF0203444
B.J. Juven, J. Kanner, F. Schved, H. Weisslowicz, Factors that interact with the antibacterial action of thyme essential oil and its active constituents Journal of Applied Microbiology. ,vol. 76, pp. 626- 631 ,(1994) , 10.1111/J.1365-2672.1994.TB01661.X
Hans H. Stein, Experience of feeding pigs without antibiotics: a European perspective. Animal Biotechnology. ,vol. 13, pp. 85- 95 ,(2002) , 10.1081/ABIO-120005772
Deborah Currie, Lorraine Lynas, D. Glenn Kennedy, W. John McCaughey, Evaluation of a modified EC Four Plate Method to detect antimicrobial drugs. Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment. ,vol. 15, pp. 651- 660 ,(1998) , 10.1080/02652039809374694
MT Roe, SD Pillai, Monitoring and identifying antibiotic resistance mechanisms in bacteria Poultry Science. ,vol. 82, pp. 622- 626 ,(2003) , 10.1093/PS/82.4.622
A. Ultee, E. P. W. Kets, E. J. Smid, Mechanisms of action of carvacrol on the food-borne pathogen Bacillus cereus. Applied and Environmental Microbiology. ,vol. 65, pp. 4606- 4610 ,(1999) , 10.1128/AEM.65.10.4606-4610.1999