Cerebrovascular reserve capacity in patients with occlusive cerebrovascular disease: assessment with dynamic susceptibility contrast-enhanced MR imaging and the acetazolamide stimulation test.

摘要: PURPOSE: To quantitatively assess cerebrovascular reserve capacity in patients with occlusive disease. MATERIALS AND METHODS: In 21 symptomatic disease, magnetic resonance (MR) imaging was performed a 1.5-T system. Before, during, and after brief bolus injection of gadopentetate dimeglumine into the antecubital vain, series 32 rapid T2*-weighted gradient-echo images two different sections were acquired simultaneously to measure concentration-time-curves brain tissue brain-feeding arteries. Principles indicator dilution analysis applied compute regional cerebral blood flow (rCBF) volume. Each patient underwent examinations, first before second acetazolamide stimulation. RESULTS: asymptomatic hemisphere, mean increase rCBF value 47.1% observed affected areas statistically significantly red...