Effect of neoadjuvant cetuximab, capecitabine, and radiotherapy for locally advanced rectal cancer: results of a phase II study
作者： Pei-Long Sun , Bing Li , Qi-Fa Ye
DOI: 10.1007/S00384-012-1446-2
关键词:
摘要: Purpose The aim of this study was to investigate the efficacy and safety neoadjuvant cetuximab, capecitabine, radiotherapy for patients with locally advanced rectal cancer.
springer.com
sci-hub.se 参考文章(37)
D Sebag-Montefiore, R Glynne-Jones, S Falk, H M Meadows, T Maughan, A phase I/II study of oxaliplatin when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group (CCOG) study British Journal of Cancer. ,vol. 93, pp. 993- 998 ,(2005) , 10.1038/SJ.BJC.6602818
A. Jemal, R. Siegel, E. Ward, T. Murray, J. Xu, C. Smigal, M. J. Thun, Cancer statistics, 2006. CA: A Cancer Journal for Clinicians. ,vol. 56, pp. 106- 130 ,(2006) , 10.3322/CANJCLIN.56.2.106
I Craven, A Crellin, R Cooper, A Melcher, P Byrne, D Sebag-Montefiore, Preoperative radiotherapy combined with 5 days per week capecitabine chemotherapy in locally advanced rectal cancer. British Journal of Cancer. ,vol. 97, pp. 1333- 1337 ,(2007) , 10.1038/SJ.BJC.6604042
Ralf-Dieter Hofheinz, Karoline Horisberger, Christoph Woernle, Frederik Wenz, Uta Kraus-Tiefenbacher, Georg Kähler, Dietmar Dinter, Rainer Grobholz, Steffen Heeger, Stefan Post, Andreas Hochhaus, Frank Willeke, Phase I trial of cetuximab in combination with capecitabine, weekly irinotecan, and radiotherapy as neoadjuvant therapy for rectal cancer International Journal of Radiation Oncology Biology Physics. ,vol. 66, pp. 1384- 1390 ,(2006) , 10.1016/J.IJROBP.2006.07.005
Jesper G. Eriksen, Torben Steiniche, Jens Overgaard, The influence of epidermal growth factor receptor and tumor differentiation on the response to accelerated radiotherapy of squamous cell carcinomas of the head and neck in the randomized DAHANCA 6 and 7 study Radiotherapy and Oncology. ,vol. 74, pp. 93- 100 ,(2005) , 10.1016/J.RADONC.2004.12.018
Rob Glynne-Jones, Suzy Mawdsley, Mark Harrison, Cetuximab and chemoradiation for rectal cancer--is the water getting muddy? Acta Oncologica. ,vol. 49, pp. 278- 286 ,(2010) , 10.3109/02841860903536010
V. Velenik, J. Ocvirk, I. Oblak, F. Anderluh, A phase II study of cetuximab, capecitabine and radiotherapy in neoadjuvant treatment of patients with locally advanced resectable rectal cancer Ejso. ,vol. 36, pp. 244- 250 ,(2010) , 10.1016/J.EJSO.2009.12.002
Federica Bertolini, Silvana Chiara, Carmelo Bengala, Paolo Antognoni, Cristina Dealis, Sandra Zironi, Norma Malavasi, Tindaro Scolaro, Roberta Depenni, Gordana Jovic, Claudia Sonaglio, Aldo Rossi, Gabriele Luppi, Pier Franco Conte, None, Neoadjuvant Treatment With Single-Agent Cetuximab Followed by 5-FU, Cetuximab, and Pelvic Radiotherapy: A Phase II Study in Locally Advanced Rectal Cancer International Journal of Radiation Oncology*Biology*Physics. ,vol. 73, pp. 466- 472 ,(2009) , 10.1016/J.IJROBP.2008.04.065
Jordi Giralt, Manuel de las Heras, Laura Cerezo, Aranzazu Eraso, Edurado Hermosilla, Dolores Velez, Juan Lujan, Eloi Espin, Jose Rossello, Joaquin Majó, Sergi Benavente, Manel Armengol, I. de Torres, The expression of epidermal growth factor receptor results in a worse prognosis for patients with rectal cancer treated with preoperative radiotherapy: a multicenter, retrospective analysis Radiotherapy and Oncology. ,vol. 74, pp. 101- 108 ,(2005) , 10.1016/J.RADONC.2004.12.021
D Koeberle, R Burkhard, R von Moos, R Winterhalder, V Hess, F Heitzmann, T Ruhstaller, L Terraciano, J Neuweiler, G Bieri, C Rust, M Toepfer, Phase II study of capecitabine and oxaliplatin given prior to and concurrently with preoperative pelvic radiotherapy in patients with locally advanced rectal cancer. British Journal of Cancer. ,vol. 98, pp. 1204- 1209 ,(2008) , 10.1038/SJ.BJC.6604297