The Old and New Methods of Assessing Kidney Function

摘要: Chronic kidney disease is a worldwide problem. Accurate assessment of function important for defining stages and assisting with drug dosing. Glomerular filtration rate (GFR) good index the health kidney. Although measured GFR using an exogenous substance most accurate, it difficult to obtain due cost resources. Equations calculating creatinine clearance estimated as measure have been developed serum marker function. The Cockcroft-Gault, Modification Diet in Renal Disease, Kidney Disease Epidemiology Collaboration equations shown statistically significant differences estimating various populations. Drug-dosing adjustments based on may differ. However, without clinical outcome data, yet be determined whether these are clinically significant.