Looping and reconfiguration dynamics of a flexible chain with internal friction

摘要: In recent past, experiments and simulations have suggested that apart from the solvent friction, friction arising protein itself plays an important role in folding by affecting intra-chain loop formation dynamics. This is termed as internal literature. Using a flexible Gaussian chain with we analyze reconfiguration times for all three topology classes namely end-to-end, end-to-interior interior-to-interior. nutshell, bypassing expensive show how simple models like of Rouse Zimm can support single molecule experiment computer simulation results on diffusion coefficients, looping time even predict effects tail length time.