Cloned defective interfering influenza A virus

作者: Nigel Dimmock

DOI:

关键词:

摘要: Cloned, i.e. defined, defective interfering (DI) influenza A virus is produced in embryonated hens eggs using a method which generates large quantities of DI material. Cloned then used tests on mice and ferrets given lethal challenge wild-type virus. When cloned co-administered with dose virulent virus, are protected compared to control inactivated Mice survived the administration infective three weeks later still against Control received only no not

参考文章(35)
D. P. Nayak, T. M. Chambers, R. K. Akkina, Defective-interfering (DI) RNAs of influenza viruses: origin, structure, expression, and interference. Current Topics in Microbiology and Immunology. ,vol. 114, pp. 103- 151 ,(1985) , 10.1007/978-3-642-70227-3_3
Ron A.M. Fouchier, Albert D.M.E. Osterhaus, Monique I.J. Spronken, Emmie De Wit, Defective influenza virus particles ,(2005)
Nigel Dimmock, Defective interfering virus ,(2007)
Doris M. Graham, S. Fazekas de St.Groth, The Production of Incomplete Virus Particles among Influenza Strains: Experiments in Eggs. British journal of experimental pathology. ,vol. 35, pp. 60- 74 ,(1954)
Colin John Hunter, Improved leaching of base metals ,(2005)
Yoshihiro Kawaoka, Gabriele Neumann, Recombinant influenza viruses for vaccines and gene therapy ,(2000)
Jerry R. McGhee, Jiri Mestecky, Mark T. Dertzbaugh, John H. Eldridge, Masatomo Hirasawa, Hiroshi Kiyono, The mucosal immune system : from fundamental concepts to vaccine development Vaccine. ,vol. 10, pp. 75- 88 ,(1992) , 10.1016/0264-410X(92)90021-B
Christopher Cane, Nigel J. Dimmock, Intracellular stability of the gene encoding influenza virus haemagglutinin. Virology. ,vol. 175, pp. 385- 390 ,(1990) , 10.1016/0042-6822(90)90423-O
Preben Magnus, The in ovo production of incomplete virus by B-Lee and A-PR8 influenza viruses. Archives of Virology. ,vol. 17, pp. 414- 423 ,(1965) , 10.1007/BF01241196
A. Mann, A.C. Marriott, S. Balasingam, R. Lambkin, J.S. Oxford, N.J. Dimmock, Interfering vaccine (defective interfering influenza A virus) protects ferrets from influenza, and allows them to develop solid immunity to reinfection Vaccine. ,vol. 24, pp. 4290- 4296 ,(2006) , 10.1016/J.VACCINE.2006.03.004