The Impact of SARS-CoV-2 Infection on the Development of Neurodegeneration in Multiple Sclerosis.

作者: Marcin Niemcewicz , Elzbieta Miller , Michal Bijak , Joanna Saluk-Bijak , Angela Dziedzic

DOI: 10.3390/IJMS22041804

关键词:

摘要: The novel coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome 2 (SARS-CoV-2), remains a global challenge. Currently, there is some information on the consequences of COVID-19 infection in multiple sclerosis (MS) patients, as it newly discovered coronavirus, but its far-reaching effects participation neurodegenerative diseases seem to be significant. Recent cases reports showed that SARS-CoV-2 may responsible for initiating demyelination process people who previously had no symptoms associated with any nervous system disorders. It presently known evokes cytokine storm syndrome, which one factors leading cerebrovascular disease. One substantial problems coexistence and MS an individual's life span. Epidemiological studies enhanced risk death rate from vascular disabilities patients approximately 30%. has been demonstrated usually show increased levels D-dimer, fibrinogen, C-reactive protein (CRP), overactivation blood platelets, are essential elements prothrombotic events. In this review, latest knowledge gathered during ongoing pandemic neurodegeneration processes discussed.

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