Histone Deacetylase Inhibitors Resensitize EGFR/EGFRvIII-Overexpressing, Erlotinib-Resistant Glioblastoma Cells to Tyrosine Kinase Inhibition

作者: Katrin Liffers , Katarina Kolbe , Manfred Westphal , Katrin Lamszus , Alexander Schulte

DOI: 10.1007/S11523-015-0372-Y

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摘要: … inhibition decreases the amount of EGFR/EGFRvIII mRNA and protein in EGFR-amplified … Reduced EGFR mRNA and protein expression as a consequence of HDAC inhibition has …

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