Association of Serum Homocysteine and Coronary Heart Disease in an Iranian Urban Population
作者： Hossein Fakhrzadeh , Ramin Heshmat , Fatemeh Bandarian , Masoumeh Nouri , Bagher Larijani
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摘要: Background: Several studies have shown that elevated serum homocysteine levels are associated with an increased risk of coronary heart disease (CHD). This survey was designed to investigate the association between hyperhomocysteinemia and CHD in Iranian urban population. Methods: In a cross-sectional study, 358 residents (129 men 229 women) 17 th District Tehran, Iran aged 25-64 years old (mean 44.08 11.77 years) were assessed for ischemic (IHD) according Rose questionnaire resting electrocardiographic (ECG) analysis by Minnesota code, factors (including homocysteine) compared non-ischemic groups. Results: Crude prevalence this population 53.4%. Mean plasma total (tHcy) significantly higher than women (P = 0.001). There no significant difference mean vitamin B12, folate non- groups 0.31, 0.16 0.51, respectively). Conclusion: According results, high level tHcy itself is not factor healthy population, but it should be considered reduction patients.
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