Prognostic value of arterial pressure, endogenous vasoactive systems, and renal function in cirrhotic patients admitted to the hospital for the treatment of ascites

摘要: To identify prognostic factors in cirrhotic patients admitted to the hospital for treatment of an episode ascites, a survival analysis was performed series 139 hospitalized our Unit between 1980 and 1985. Mean follow-up 12.8 +/- 14.2 mo (mean SD). A total 38 variables based on history, physical examination, hepatic biochemical tests, renal function endogenous vasoactive systems were analyzed value. Eighteen these had value univariate analysis. multivariate (Cox's regression method) disclosed that 7 18 independent Of predictors survival, mean arterial pressure plasma norepinephrine concentration best predicted prognosis. Two other independently correlated with urinary sodium excretion glomerular filtration rate. The remaining three nutritional status, hepatomegaly, serum albumin concentration. Therefore, findings indicate that, cirrhosis parameters estimating systemic hemodynamics are better than those routinely used estimate function.