Resorption behavior of a nanostructured bone substitute: in vitro investigation and clinical application.
作者： C. Reichert , W. Götz , S. Reimann , L. Keilig , M. Hagner
DOI: 10.1007/S00056-012-0136-6
关键词:
摘要: To develop an in vitro assay for quantitative analysis of the degradation to which a bone substitute is exposed by osteoclasts. The aim establishing this method was improve predictability carrying out tooth movements via substitutes and provide basis verification exemplary clinical cases. After populating (NanoBone®; ArtOss, Germany) with osteoclastic cells, inductively-coupled mass spectrometry used evaluate changing calcium levels culture medium as marker resorption activity. It observed that increased substantially cells substitute. This valid can assist clinicians selecting appropriate materials certain patients. While occurring through material were successful, uncertainty about approach will remain long-term results are not available.
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