Synthesis and characterization of fluconazole-functionalized magnetic nanoparticles as a catalyst for the synthesis of 3-aryl and 3-amino-imidazo[1,2-a]pyridines

作者: Mohammad Jafarzadeh , Ebrahim Soleimani , Heshmatollah Sepahvand , Rohana Adnan

DOI: 10.1039/C5RA05246G

关键词:

摘要: Fluconazole was successfully immobilized on the surface of chloropropyl-modified Fe3O4–SiO2 core–shell nanoparticles and found to exhibit unique catalytic activity for synthesis 3-aryl-imidazo[1,2-a]pyridines in water. This catalyst also showed great a multi-component reaction 3-amino-imidazo[1,2-a]pyridines under solvent-free conditions. The magnetically-recoverable be capable repeated reuse without significant loss activity.

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