Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice.
作者： F. Samad , D. J. Loskutoff
DOI: 10.1007/BF03401641
关键词:
摘要: Background Although elevated plasminogen activator inhibitor-1 (PAI-1) is associated with obesity and may be a risk factor for cardiovascular disease, the mechanism(s) that lead to this elevation, tissue/cellular origins of increase, remain defined. In report, we have addressed these questions using genetically obese mice (ob/ob) their lean counterparts (+/?).
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