Mouse Genetic Models in Studying Adipose Angiogenesis
作者： Ilse Scroyen , H. Roger Lijnen
DOI: 10.1007/978-1-4614-8069-3_14
关键词:
摘要: Development of obesity is associated with modulation adipose tissue structure, involving adipogenesis, angiogenesis, and extracellular matrix remodeling. These processes require proteolytic activity provided mainly by the fibrinolytic, metalloproteinase, ADAM/ADAMTS systems. Adipogenesis tightly as shown findings that explants trigger blood vessel formation, whereas in turn endothelial cells promote preadipocyte differentiation. Modulation angiogenesis may have potential to impair development.
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