Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency.
作者： Darren J. Baker , Carmen Perez-Terzic , Fang Jin , Kevin S. Pitel , Nicolas J. Niederländer
DOI: 10.1038/NCB1744
关键词:
摘要: Expression of p16Ink4a and p19Arf increases with age in both rodent and human tissues. However, whether these tumour suppressors are effectors of ageing remains unclear, mainly …
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