Local Failure in Patients Treated with Radiotherapy and Multidrug Chemotherapy for Small Cell Lung Cancer

摘要: Fifty-three patients with small cell carcinoma of the lung were treated chemotherapy and radiotherapy, 40 Gy in chest tumour. Intrathoracic failure occurred 89% cases extensive disease 60% those limited disease. Since 86% all failures localized within target volume, one can conclude that most radiation dose was too low for eradication The treatment technique resulted inhomogeneities more than ±5% 45% cases. high local rate might indicate need improved first place higher dose. However, 82% 50% without also developed distant metastases. This curative potential thoracic radiotherapy probably is limited. Besides, lethal toxicity affected particularly whom cure had been achieved, indicating difficulty increasing ...