Pathologic findings in total esophagectomy specimens after intracavitary and external-beam radiotherapy

作者: Brian Berry , Roberta R. Miller , Andrew Luoma , Bill Nelems , John Hay

DOI: 10.1002/1097-0142(19891101)64:9<1833::AID-CNCR2820640913>3.0.CO;2-U

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摘要: Pathologic findings in 21 esophagectomy specimens from patients having preoperative combined intracavitary radiotherapy (ICR) and external-beam (EBR) are described. Eleven received 1500 cGY ICR 4000 cGy EBR (Group 1) ten plus 2000 to 3000 2). Effectiveness of was expressed as the ratio between depth radiation effect tumor invasion. Depth one four levels: Level I, not deeper than muscularis mucosa; 2, involving but submucosa; 3, propria; 4, periesophageal soft tissue. The damage cells comparable two groups. However, residual present tissue only 11 after high-dose compared with lower dose (P less 0.01, chi-square test). A invasion six receiving patient 0.05). authors conclude that affords good local control majority patients. Higher doses give a better layers esophageal wall. provides simple objective approach pathologic analysis specimens.

参考文章(15)
Eli Glatstein, Steven L. Hancock, Radiation therapy of esophageal cancer Seminars in Oncology. ,vol. 11, pp. 144- 158 ,(1984) , 10.5555/URI:PII:0093775484901611
Elizabeth Crist Hyden, Bryan Langholz, Timothy Tilden, Kenneth Lam, Gary Luxton, Melvin Astrahan, Joanne Jepson, Zbigniew Petrovich, External beam and intraluminal radiotherapy in the treatment of carcinoma of the esophagus. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 96, pp. 237- 241 ,(1988) , 10.1016/S0022-5223(19)35264-X
John Wong, Esophageal resection for cancer: The rationale of current practice American Journal of Surgery. ,vol. 153, pp. 18- 24 ,(1987) , 10.1016/0002-9610(87)90196-6
Ichiro Akakura, Yoshizo Nakamura, Temo Kakegawa, Ryuichi Nakayama, Hiroshi Watanabe, Hisao Yamashita, Surgery of carcinoma of the esophagus with preoperative radiation. Chest. ,vol. 57, pp. 47- 57 ,(1970) , 10.1378/CHEST.57.1.47
Mark B. Orringer, Technical Aids in Performing Transhiatal Esophagectomy without Thoracotomy The Annals of Thoracic Surgery. ,vol. 38, pp. 128- 132 ,(1984) , 10.1016/S0003-4975(10)62219-9
Yoshio Hishikawa, Midori Taniguchi, Norihiko Kamikonya, Shinichi Tanaka, Takashi Miura, External beam radiotherapy alone or combined with high-dose-rate intracavitary irradiation in the treatment of cancer of the esophagus: Autopsy findings in 35 cases Radiotherapy and Oncology. ,vol. 11, pp. 223- 227 ,(1988) , 10.1016/0167-8140(88)90004-7
Yoshio Hishikawa, Norihiko Kamikonya, Shinichi Tanaka, Takashi Miura, Radiotherapy of esophageal carcinoma: role of high-dose-rate intracavitary irradiation. Radiotherapy and Oncology. ,vol. 9, pp. 13- 20 ,(1987) , 10.1016/S0167-8140(87)80214-1