作者: Brian Berry , Roberta R. Miller , Andrew Luoma , Bill Nelems , John Hay
DOI: 10.1002/1097-0142(19891101)64:9<1833::AID-CNCR2820640913>3.0.CO;2-U
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摘要: Pathologic findings in 21 esophagectomy specimens from patients having preoperative combined intracavitary radiotherapy (ICR) and external-beam (EBR) are described. Eleven received 1500 cGY ICR 4000 cGy EBR (Group 1) ten plus 2000 to 3000 2). Effectiveness of was expressed as the ratio between depth radiation effect tumor invasion. Depth one four levels: Level I, not deeper than muscularis mucosa; 2, involving but submucosa; 3, propria; 4, periesophageal soft tissue. The damage cells comparable two groups. However, residual present tissue only 11 after high-dose compared with lower dose (P less 0.01, chi-square test). A invasion six receiving patient 0.05). authors conclude that affords good local control majority patients. Higher doses give a better layers esophageal wall. provides simple objective approach pathologic analysis specimens.