Single chemical entity legal highs: assessing the risk for long term harm.

摘要: A recent and dramatic increase in the emergence of novel psychoactive substances ('legal highs') has left many governments unable to provide a timely response an increasing number potentially harmful drugs now available public. In this rapid lawful drug use, UK government intends implement temporary class orders, whereby with potential for misuse harm can be regulated 12 month period. During period investigation harms induced by these will take place. However, short time-frame which information must gathered, paucity data on substances, means that robust pharmacological toxicological analyses may replaced extrapolating from illegal similar chemical structures. This review explores pharmacology toxicology past present 'legal highs' discusses risks failing carry out in-depth scientific research individual substances.