3D hydrogel-based microwell arrays as a tumor microenvironment model to study breast cancer growth.

作者: John Casey , Xiaoshan Yue , Trung Dung Nguyen , Aylin Acun , Victoria R Zellmer

DOI: 10.1088/1748-605X/AA5D5C

关键词:

摘要: … cell culture methods, microfabricated three-dimensional (3D) … breast cancer cells and primary mammary organoids. We … breast cancer cell line HCC1806 and primary organoids from …

参考文章(56)
Brooke N. Mason, Alina Starchenko, Rebecca M. Williams, Lawrence J. Bonassar, Cynthia A. Reinhart-King, Tuning three-dimensional collagen matrix stiffness independently of collagen concentration modulates endothelial cell behavior Acta Biomaterialia. ,vol. 9, pp. 4635- 4644 ,(2013) , 10.1016/J.ACTBIO.2012.08.007
Manjulata Singh, David A. Close, Shilpaa Mukundan, Paul A. Johnston, Shilpa Sant, Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway Activation. Assay and Drug Development Technologies. ,vol. 13, pp. 570- 583 ,(2015) , 10.1089/ADT.2015.662
Trung Dung Nguyen, Adekunle Oloyede, Sanjleena Singh, YuanTong Gu, Microscale consolidation analysis of relaxation behavior of single living chondrocytes subjected to varying strain-rates. Journal of The Mechanical Behavior of Biomedical Materials. ,vol. 49, pp. 343- 354 ,(2015) , 10.1016/J.JMBBM.2015.05.003
A. Pathak, S. Kumar, Independent regulation of tumor cell migration by matrix stiffness and confinement Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 10334- 10339 ,(2012) , 10.1073/PNAS.1118073109
Paraic A. Kenny, Genee Y. Lee, Connie A. Myers, Richard M. Neve, Jeremy R. Semeiks, Paul T. Spellman, Katrin Lorenz, Eva H. Lee, Mary Helen Barcellos-Hoff, Ole W. Petersen, Joe W. Gray, Mina J. Bissell, The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression Molecular Oncology. ,vol. 1, pp. 84- 96 ,(2007) , 10.1016/J.MOLONC.2007.02.004
Jason W. Nichol, Sandeep T. Koshy, Hojae Bae, Chang M. Hwang, Seda Yamanlar, Ali Khademhosseini, Cell-laden microengineered gelatin methacrylate hydrogels Biomaterials. ,vol. 31, pp. 5536- 5544 ,(2010) , 10.1016/J.BIOMATERIALS.2010.03.064
Lina Schukur, Pinar Zorlutuna, Jae Min Cha, Hojae Bae, Ali Khademhosseini, Directed Differentiation of Size-Controlled Embryoid Bodies Towards Endothelial and Cardiac Lineages in RGD-Modified Poly(Ethylene Glycol) Hydrogels Advanced Healthcare Materials. ,vol. 2, pp. 195- 205 ,(2013) , 10.1002/ADHM.201200194
YOSHINORI IMAMURA, TORU MUKOHARA, YOHEI SHIMONO, YOHEI FUNAKOSHI, NAOKO CHAYAHARA, MASANORI TOYODA, NAOMI KIYOTA, SHINTARO TAKAO, SEISHI KONO, TETSUYA NAKATSURA, HIRONOBU MINAMI, Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer Oncology Reports. ,vol. 33, pp. 1837- 1843 ,(2015) , 10.3892/OR.2015.3767
Jimmie E. Fata, Hidetoshi Mori, Andrew J. Ewald, Hui Zhang, Evelyn Yao, Zena Werb, Mina J. Bissell, The MAPKERK-1,2 pathway integrates distinct and antagonistic signals from TGFα and FGF7 in morphogenesis of mouse mammary epithelium Developmental Biology. ,vol. 306, pp. 193- 207 ,(2007) , 10.1016/J.YDBIO.2007.03.013