Influence of Intention to Adhere, Beliefs and Satisfaction About Medicines on Adherence in Solid Organ Transplant Recipients

摘要: Introduction Nonadherence to immunosuppressive (IS) therapy is associated with poor outcomes. Identifying factors predicting adherence therefore essential. The primary objective of this study was test whether parameters a model adapted from the theory planned behavior, and more specifically attitudes that are influenced by beliefs satisfaction medication, could predict in solid organ transplant patients. Methods Adherence assessed self-reported medication scale IS blood trough concentrations over 6 months, four units. Satisfaction were using Treatment Medicines Questionnaire (SATMED-Q) Beliefs about (BMQ), respectively. Theory behavior specific questionnaire exploring intentions, subjective norms, perceived behavioral control. characteristics socioeconomic data also collected. Results One hundred fifty-three patients enrolled, including lung (n=33), heart (n=43), liver (n=42), kidney (n=44) positive higher adherent than those nonadherent Factors independently an increased risk nonadherence negative general medications (odds ratio [OR]=0.89 [0.83-0.97]), living alone (OR=2.78 [1.09-7.09]), transplantation (OR=3.49 [1.34-9.09]), being on everolimus (OR=5.02 [1.21-20.8]). Conclusion Negative toward shown be independent factor adherence. Therefore, BMQ effective, easy implement tool, for use everyday practice, identify needing interventions improve IS.