Relationship between exhaled nitric oxide and the frequency of severe acute exacerbation of COPD: 3-year follow-up.

摘要: In a recent trial we have assessed fractional exhaled nitric oxide (FENO) in cohort of patients with an acute exacerbation chronic obstructive pulmonary disease (COPD). the current study retrospectively investigated frequency severe hospitalization-associated exacerbations same over 3 years after initial FENO measurement. A total 58 COPD were enrolled and allocated either into low (< 27 ppb) or high (≥ group depending on their level at exacerbation. Beside annual rate exacerbations, sputum culture results antibiotic treatments also analyzed during follow-up. Both number per patient-year hospitalization days due to significantly increased from compared those group. Sputum samples derived more frequently indicative bacterial infection obtained other subgroup. Also, was subjects Results this pilot suggest that diverse risks for future levels