Hypoxia-inducible factors are required for chemotherapy resistance of breast cancer stem cells

作者: Debangshu Samanta , Daniele M. Gilkes , Pallavi Chaturvedi , Lisha Xiang , Gregg L. Semenza

DOI: 10.1073/PNAS.1421438111

关键词:

摘要: … HIF-1 has been implicated in resistance to chemotherapy (16, 17) and in hypoxic colon … of multidrug resistance 1 (MDR1) (18), which mediates efflux of chemotherapy from cancer cells …

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