Improvement single-wall carbon nanotubes (SWCNTs) based on functionalizing with monomers 2-hydroxyethylmethacryate (HEMA) and N-vinylpyrrolidone (NVP) for pharmaceutical applications as cancer therapy
作者： Fatemeh Abbaszadeh , Omid Moradi , Mehdi Norouzi , Omid Sabzevari
DOI: 10.1016/J.JIEC.2013.11.025
关键词:
摘要: Abstract The functionalized carbon nanotubes play significant roles in the fields such as preparation of composite materials and biological technologies. This paper explains covalent functionalization single-wall (SWCNTs) with biomedical important monomers, 2-hydroxyethylmethacryate (HEMA) N-vinylpyrrolidone (NVP) by chemical grafting HEMA PVP monomers via free radical polymerization. To get carboxylic acid SWCNTs, first were oxidized a mixture nitric sulfuric (1:3). Then, binding NVP onto surface SWCNTs was performed HEMA, chloride-bound nanotube esterification reaction. These results confirmed FT-IR SEM. cell culture experiments conducted for pharmaceutical applications used cancer therapy.
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