Cold acclimation-recruited nonshivering thermogenesis: the Syrian hamster is not an exception

摘要: Biochemical evidence from in vitro studies of brown adipose tissue Syrian hamsters indicates a significant degree recruitment the as an effect cold acclimation. However, earlier vivo indicate lack nonshivering thermogenesis intact animal result Because this apparent discrepancy, occurrence acclimation-recruited was investigated. Hamsters were acclimated to 6 degrees C or remained at 24 (controls), and their thermogenic response investigated open-circuit system C. Cold acclimation resulted small increase resting metabolic rate major norepinephrine (61% over controls 156% cold-acclimated animals). The absolute beta 3-specific adrenergic agonist CGP-12177 also induced high thermogenesis, which similarly recruited. It concluded that, concerning relative on capacity for responded would be predicted experiments. Thus hamster does not seem constitute exception general patterns described other rodents due