Childhood Sexual Abuse and Adult Psychiatric and Substance Use Disorders in Women

摘要: Background Women who report childhood sexual abuse (CSA) are at increased risk for developing psychiatric disorders in adulthood. What is the diagnostic specificity and cause of this association? Methods In a population-based sample 1411 female adult twins, 3 levels CSA were assessed by self-report cotwin report: nongenital, genital, intercourse. Interviews with twins parents family background diagnoses substance dependence disorders. Odds ratios (ORs) calculated logistic regression. Results By self-report, 30.4% reported any 8.4% Self-reported was positively associated all disorders, highest ORs being seen bulimia alcohol other drug dependence. The modest often nonsignificant nongenital genital especially intercourse, where most exceeded 3.0. A similar pattern findings as cotwin, although many smaller. Controlling factors parental psychopathology produced small to reduction ORs. twin pairs discordant CSA, exposed consistently higher illness. Conclusions have substantially wide range psychopathology. Most association due more severe forms cannot be explained familial factors. Although biases ruled out, these results consistent hypothesis that causally related an