Distribution of immunoreactive growth hormone releasing factor (1–44)NH2 in the tuberoinfundibular system of the rhesus monkey

作者: Ronald M. Lechan , Hong D. Lin , Nicholas Ling , Ivor M.D. Jackson , Stanley Jacobson

DOI: 10.1016/0006-8993(84)91010-2

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摘要: Abstract Using an antiserum which reacts with the carboxyl terminus of GRF(1–44)NH 2 , distribution immunoreactive growth hormone releasing factor (GRF) in rhesus monkey hypothalamus was delineated by peroxidase immunocytochemistry. Immunoreactive material present dense terminal fields median eminence closely associated portal capillaries but a location distinct from that noted for thyrotropin-releasing (TRH) or somatostatin. GRF-immunoreactive cell bodies were identified arcuate nucleus and ventromedial nucleus. These studies provide evidence presence primate brain demonstrate it is localized exclusively cells fibers corresponding to tuberoinfundibular system.

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