CD109 is a novel marker for squamous cell/adenosquamous carcinomas of the gallbladder
作者： Fengyun Dong , Chuanfeng Lu , Xiaocui Chen , Yuan Guo , Ju Liu
DOI: 10.1186/S13000-015-0375-0
关键词:
摘要: Gallbladder cancer is the most common biliary tract malignancy with worst overall prognosis. CD109 a co-receptor of TGF-β1 and suppresses TGF-β signaling. In this study, protein expression in three subtypes gallbladder was examined by immunohistochemistry on human tissue samples microarrays. We found that specifically expressed malignant squamous cells cell carcinomas (86.7 %) adenosquamous (91.7 %), but not adenocarcinomas or normal tissues. Thus, may be potential pathology marker for cell/adenosquamous carcinomas.
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