The Therapeutic Targeting Of Folate Receptor Alpha Positive Tumors Via Folate Receptor Selective Novel 5- And 6- Substituted Pyrrolo [2,3-D]pyrimidine Antifolates"
作者： Shermaine Kimberly Mitchell-Ryan
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参考文章(125)
Kevin E. Brigle, Michael J. Spinella, Esteban E. Sierra, I. David Goldman, Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line. Journal of Biological Chemistry. ,vol. 270, pp. 22974- 22979 ,(1995) , 10.1074/JBC.270.39.22974
Daniel Sanghoon Shin, Rongbao Zhao, Andras Fiser, David I Goldman, None, Functional roles of the A335 and G338 residues of the proton-coupled folate transporter (PCFT-SLC46A1) mutated in hereditary folate malabsorption. American Journal of Physiology-cell Physiology. ,vol. 303, ,(2012) , 10.1152/AJPCELL.00171.2012
Donald D. Anderson, Patrick J. Stover, SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis PLoS ONE. ,vol. 4, pp. e5839- ,(2009) , 10.1371/JOURNAL.PONE.0005839
Anne S. Tibbetts, Dean R. Appling, Compartmentalization of mammalian folate-mediated one-carbon metabolism. Annual Review of Nutrition. ,vol. 30, pp. 57- 81 ,(2010) , 10.1146/ANNUREV.NUTR.012809.104810
Paul S. Meltzer, Rui He, Kenneth H. Cowan, Sarah L. Anzick, Katharine H. Dixon, Magdalene K. Sgagias, Maokai Gong, Jeffrey A. Moscow, Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells. Cancer Research. ,vol. 55, pp. 3790- 3794 ,(1995)
Robert Steinfeld, Marcel Grapp, Ralph Kraetzner, Steffi Dreha-Kulaczewski, Gunther Helms, Peter Dechent, Ron Wevers, Salvatore Grosso, Jutta Gärtner, Folate Receptor Alpha Defect Causes Cerebral Folate Transport Deficiency: A Treatable Neurodegenerative Disorder Associated with Disturbed Myelin Metabolism American Journal of Human Genetics. ,vol. 85, pp. 354- 363 ,(2009) , 10.1016/J.AJHG.2009.08.005
X L Sun, B R Murphy, Q J Li, S Gullapalli, J Mackins, H N Jayaram, A Srivastava, A C Antony, Transduction of folate receptor cDNA into cervical carcinoma cells using recombinant adeno-associated virions delays cell proliferation in vitro and in vivo. Journal of Clinical Investigation. ,vol. 96, pp. 1535- 1547 ,(1995) , 10.1172/JCI118192
A C Antony, R A Briddell, J E Brandt, J E Straneva, R S Verma, M E Miller, L A Kalasinski, R Hoffman, Megaloblastic hematopoiesis in vitro. Interaction of anti-folate receptor antibodies with hematopoietic progenitor cells leads to a proliferative response independent of megaloblastic changes. Journal of Clinical Investigation. ,vol. 87, pp. 313- 325 ,(1991) , 10.1172/JCI114989
Xuan Zheng, Karen Kelley, Hala Elnakat, Wu Yan, Ted Dorn, Manohar Ratnam, mRNA Instability in the Nucleus Due to a Novel Open Reading Frame Element Is a Major Determinant of the Narrow Tissue Specificity of Folate Receptor α Molecular and Cellular Biology. ,vol. 23, pp. 2202- 2212 ,(2003) , 10.1128/MCB.23.6.2202-2212.2003
Daniel J O’Shannessy, Elizabeth B Somers, Leslie M Palmer, Robert P Thiel, Pankaj Oberoi, Ryan Heath, Lisa Marcucci, Serum folate receptor alpha, mesothelin and megakaryocyte potentiating factor in ovarian cancer: association to disease stage and grade and comparison to CA125 and HE4 Journal of Ovarian Research. ,vol. 6, pp. 29- 29 ,(2013) , 10.1186/1757-2215-6-29