Usefulness of pulsed-field gel electrophoresis in tracking two outbreaks of invasive meningococcal disease serogroup C in British Columbia.
作者： Grahame Quan , Mark Gilbert , Samara T David , Tazim Rahim , Kathy Adie
DOI: 10.1155/2007/295973
关键词:
摘要: Two major outbreaks of invasive meningococcal disease serogroup C (IMD-C) were identified in British Columbia between 2000 and 2004. Pulsed-field gel electrophoresis (PFGE) porA gene sequencing all retained IMD-C isolates used to assess correlations genotypes epidemiological patterns. PFGE patterns correlated with 2004 Columbia, demonstrated that can identify outbreak-related cases. Both a respective pattern. analysis the outbreak strain men who have sex was closely related 2001 Abbotsford strain. PorA data indicated low diversity class 1 outer membrane proteins did not correlate trends. There trend for outbreak-associated types demonstrate higher case fatality rates.
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