Comparative Study of Intralesional Dexamethasone, Hyaluronidase and Oral Pentoxifylline in Patients with Oral Submucous Fibrosis

作者: Venkat Reddy M , Sreekanth K , Ibrahim M , C Vani , Satishkumar Gp

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摘要: Back ground : Oral submucous fibrosis (OSF) is characterized by excessive production of collagen leading to inelasticity the oral mucosa and atrophic changes epithelium. Aim study clinically evaluate efficacy Pentoxifylline 400 mg tablets in comparison intralesional injections Dexamethasone (4mg/ml) Hyaluronidase 1500 IU 0.5 ml Lignocaine 2% management OSF patients. Methodology The population consisted 40 male patients with OSF. Patients were divided into two groups. 20 are pentoxifylline group group. Group received twice daily for first 4 weeks thrice next 8 weeks. biweekly (4mg/ml), a period 12 Parameters taken burning sensation, mouth opening, tongue protrusion cheek flexibility.

参考文章(11)
Rajendran R, Oral Submucous Fibrosis: Etiology, Pathogenesis, and Future Research Bulletin of The World Health Organization. ,vol. 72, pp. 985- 996 ,(1994)
P. R. Murti, R. B. Bhonsle, P. C. Gupta, D. K. Daftary, J. J. Pindborg, Fali S. Mehta, Etiology of oral submucous fibrosis with special reference to the role of areca nut chewing Journal of Oral Pathology & Medicine. ,vol. 24, pp. 145- 152 ,(1995) , 10.1111/J.1600-0714.1995.TB01156.X
K. Ranganathan, M. Uma Devi, Elizabeth Joshua, K. Kirankumar, T. R. Saraswathi, Oral submucous fibrosis: a case-control study in Chennai, South India. Journal of Oral Pathology & Medicine. ,vol. 33, pp. 274- 277 ,(2004) , 10.1111/J.0904-2512.2004.00116.X
J. Waal, A. Olivier, C. W. Wyk, J. S. Maritz, The fibroblast population in oral submucous fibrosis Journal of Oral Pathology and Medicine. ,vol. 26, pp. 69- 74 ,(1997) , 10.1111/J.1600-0714.1997.TB00024.X
J.J. Pindborg, R.B. Bhonsle, P.R. Murti, P.C. Gupta, D.K. Daftary, Fali S. Mehta, Incidence and early forms of oral submucous fibrosis Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 50, pp. 40- 44 ,(1980) , 10.1016/0030-4220(80)90329-1
N. G. El-Labban, J. P. Canniff, Ultrastructural findings of muscle degeneration in oral submucous fibrosis Journal of Oral Pathology & Medicine. ,vol. 14, pp. 709- 717 ,(1985) , 10.1111/J.1600-0714.1985.TB00550.X
Jens J. Pindborg, Satyavati M. Sirsat, Oral submucous fibrosis. Oral Surgery, Oral Medicine, Oral Pathology. ,vol. 22, pp. 764- 779 ,(1966) , 10.1016/0030-4220(66)90367-7
D. R. Lai, H. R. Chen, L. M. Lin, Y. L. Huang, C. C. Tsai, Der-Rong Lai, Clinical evaluation of different treatment methods for oral submucous fibrosis. A 10‐year experience with 150 cases Journal of Oral Pathology & Medicine. ,vol. 24, pp. 402- 406 ,(1995) , 10.1111/J.1600-0714.1995.TB01209.X
Sinor Pn, Bhonsle Rb, Mehta Hc, Gupta Pc, Pawar Vs, Oral submucous fibrosis in India: A new epidemic? The National Medical Journal of India. ,vol. 11, pp. 113- ,(1998)
Deepak Gupta, SC Sharma, None, Oral submucous fibrosis—A new treatment regimen Journal of Oral and Maxillofacial Surgery. ,vol. 46, pp. 830- 833 ,(1988) , 10.1016/0278-2391(88)90043-2