Transcranial Direct Current Stimulation in Poststroke Aphasia Recovery

摘要: Transcranial direct current stimulation (tDCS), a form of noninvasive brain originally studied for its effect on motor limb physiology,1 has been investigated use in the treatment aphasia since 2008.2–3 The experimental tDCS aphasia, however, began differently from those paradigms established poststroke recovery, both conceptually and method. Not only is research relative newcomer to field experimentation, it thus far somewhat an outlier limited autonomously. Theoretically understood be vastly more complex than our intricate systems, cortical language representation most recently conceptualized as dual stream, diffuse network,4–6 with processing subcomponents evolved nonlinguistic primates.7,8 In stream model, human functions are lateralized primarily left hemisphere, Broca’s area comprising complement bilateral dorsal network devoted naming articulation. Conversely, Wernicke’s constitutes origin ventral which semantic meaning attached components speech sounds.6,9–21 Additional activation homologous right hemisphere areas seems determined by lexical necessity, increased articulatory demands activated within decoding unfamiliar words network.9 Complex may optimally prime cortex rehabilitation using tDCS, considered even challenging modulate plexus encodes produces all richness. theoretical mechanisms during protocols suggest that primes enhanced outcomes behavioral therapies,22 have led appeal combining methods concurrently. …