Axillary granular parakeratosis
作者： Alan D. Northcutt , Donna M. Nelson , Jaime A. Tschen
DOI: 10.1016/0190-9622(91)70078-G
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摘要: The term axillary granular parakeratosis is proposed for a unique eruption with distinct histopathologic features. Four middle-aged to elderly patients (three women, one man) had unilateral or bilateral, usually pruritic, hyperpigmented bright red patches in the axillae. Biopsy specimens revealed severe compact stratum corneum measuring 80 250 μm maximal thickness, maintenance of granulosum, remarkable retention keratohyaline granules throughout corneum, and vascular proliferation ectasia. A contact reaction an antiperspirant/deodorant suspected as cause. We speculate that offending agent alters maturation sequence granulosum possibly by interfering degradation filag-grin precursor filaggrin units.
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Jytte Roed-Petersen, Gunnar Auken, Niels Hjorth, Contact sensitivity to Irgasan DP 300. Contact Dermatitis. ,vol. 1, pp. 293- 294 ,(1975) , 10.1111/J.1600-0536.1975.TB05439.X
Edward Shmunes, Quaternary Ammonium Compound Contact Dermatitis From a Deodorant Archives of Dermatology. ,vol. 105, pp. 91- 93 ,(1972) , 10.1001/ARCHDERM.1972.01620040059014
Peter J. Panagotacos, Allergic Contact Dermatitis to Vitamin E Aerosol Deodorant Archives of Dermatology. ,vol. 108, pp. 579- 580 ,(1973) , 10.1001/ARCHDERM.1973.01620250059023
Wilfred Minkin, Contact Dermatitis From Deodorants Archives of Dermatology. ,vol. 107, pp. 774- 775 ,(1973) , 10.1001/ARCHDERM.1973.01620200080027
Louise B. Aust, H. I. Maibach, Incidence of human skin sensitization to isostearyl alcohol in two separate groups of panelists. Contact Dermatitis. ,vol. 6, pp. 269- 271 ,(1980) , 10.1111/J.1600-0536.1980.TB04928.X
C. D. Calnan, Dihydroxydichlorodiphenylmonosulphide in a deodorant. Contact Dermatitis. ,vol. 1, pp. 127- 128 ,(1975) , 10.1111/J.1600-0536.1975.TB05351.X
Jan E. Wahlberg, Routine patch testing with Irgasan DP 300® Contact Dermatitis. ,vol. 2, pp. 292- 292 ,(1976) , 10.1111/J.1600-0536.1976.TB03058.X
A Gedeon Matoltsy, Desmosomes, Filaments, And Keratohyaline Granules: Their Role In The Stabilization And Keratinization of The Epidermis Journal of Investigative Dermatology. ,vol. 65, pp. 127- 142 ,(1975) , 10.1111/1523-1747.EP12598093
Kurt Stenn, Beverly A. Dale, Filaggrin, the matrix protein of keratin. American Journal of Dermatopathology. ,vol. 7, pp. 65- 68 ,(1985) , 10.1097/00000372-198502000-00014
Przybilla B, Ring J, Schwab U, Hölzle E, Contact sensitization to an antiperspirant with the active ingredient propantheline bromide Hautarzt. ,vol. 34, pp. 459- 462 ,(1983)